I think the optimum ratio for combustion of gasoline is 14:1, but this is when it burns the hottest and is not good on your engine. I am sure Toyota's ECUs are not designed to run anywhere near 14:1, so like Todd said a 5% leaner mixture on a NA engine is likely not going to hurt anything. In fact, I think this 5% leaner mixture may be where you get some of that added horsepower.
Again I am no expert, but from what research I've done, proper headers actually "suck" (proper term is "scavenge") the exhaust gasses out of the cylinder, leaving more room for fresh intake air. The more air, the leaner the mixture. It is not necessarily more volume of air, but the fact that less already burned oxygen by-products are present, the higher the volume of fresh air that can replace it.
Todd can attest to this. On aircraft you have a mixture control thrown into the mix (not on the Rans Coyote I am in love with as this is injected, but the Cessna 150, 152, and 172's I used to fly). You get your max power, and notice an RPM increase, as you lean it back to 14:1. Beyond 14:1, the engine will eventually stall.
However, this will start to raise your oil temp, cylinder head temps, and will eventually burn out the valves and so on. I think if you tried to run a stock ECU with boost and headers you would definitely burn stuff. Way too much air and the ECU is only programmed to do so much. This is where companies like URD really come into play saving our @$$es. Everytime you mod something, something has to give. "For every action there is an equal and opposite reaction." We recently found this out the hard way on the trail when my buddy's 4Runner snapped a shackle off of his axle because we got him 1.5" more travel and overlooked his upper control arm play... Oops. Sorry Dan!
Oh yeah. That shackle decided if it was going down, it was taking his brake line with it.

That was fun... did we ever get the pics up here of the Nissan Xterra towing two Toyota's? (I was the rear tether for down hills...)